Nucleoside
Future Medicine is
a company specializing in the development of nucleoside-based new drug
Future Medicine is a company specializing in the development of nucleoside-based new drug
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01
A nucleoside is an important endogenous substance that is Indispensable for the survival of all living things, including humans, viruses, and bacteria; Involved in DNA/RNA Replication, cell signaling system, and maintenance of Homeostasis
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02
Its therapeutic implication holds promises for the treatment of various diseases Such as Cancer, Neuronal and Cardiovascular disease as well as inflammatory, viral and bacterial infection
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03
It is characterized by Good cell permeability due to nucleoside transporter; Lesser manifestation of species differences which escalates replicability to promising clinical efficacy Practicability in the back-up derivatization through structural modification; High target specificity
Excellent choice for new drug R&D
1st and 2nd Generation of Antiviral/Anticancer Nucleoside Drugs
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Zidovudine/HIV
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Remdesivir/COVID-19
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Entecavir/HBV
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Gemcitabine/췌장암
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Sofosbuvir/HCV
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Molnupiravir/COVID-19
Future Medicines new drug R&D using 3rd and 4th Nucleosides
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FM101
Anti-Inflammatory/Fibrotic effect Mediated by modulation of abnormal cell signaling via A3AR -
FM203
Anti-viral Inhibition of DNA/RNA polymerase, Transmethylase, and SAH hydrolase to suppress viral replication -
FM301
Novel target cancer drug Anti-cancer drug inhibiting novel target, HASPIN -
FM401
Immuno-oncology Prevention of Adenosines binding to A2AAR on immune cell to preserve its turmor killing effet